Course catalogue doctoral education - VT19

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Title Basic inflammation
Course number 2705
Programme Allergi, immunologi och inflammation (Aii)
Language English
Credits 3.0
Date 2018-09-17 -- 2018-10-10
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements Documented knowledge about basic concepts of innate and adaptive immunity (e.g. immunology course during undergraduate education)
Purpose of the course This course will give a general and broad overview knowledge in the field of inflammation. Ability to think critically will be encouraged during discussions and group work.
Intended learning outcomes After the course, the participant will be able to: understand cellular and molecular events those underlie the initiation, progression and resolution of inflammation; to describe the principal cell types involved in inflammatory responses and their interactions, the regulation of inflammation by inflammatory mediators, and the mechanisms of resolution and tissue repair; to understand the interplay between acute and chronic inflammation in the context of chronic inflammatory diseases and describe anti-inflammatory treatment strategies.
Contents of the course The course provides the current concept of inflammation and consists of two parts. Part 1 will cover the basic mechanisms and mediators of inflammation (host defence peptides, coagulation, complement, alarmins, lipid mediators, the acute phase proteins, inflammatory cells), non-resolving inflammation, resolution of inflammation. Part 2 will discuss the common and specific features of inflammatory diseases (sepsis, chronic inflammatory diseases), animal models of inflammation, role of genetic and environmental factors, anti-inflammatory treatment. At the end of the course the students will present projects and write web-based exam.
Teaching and learning activities Lectures, journal clubs, small-group work with a project, discussions and the project presentation, studying the course literature. The course is full-time for six days separated into two parts and also includes the non-scheduled time (32h) between the parts for the project work including meetings with mentors and the course literature studies.
Compulsory elements The project work, student attendance at the project presentations and the web-based exam are mandatory.
Examination Oral presentations of the small-group projects, all students have to participate actively in the presentation and discussion. Web-based written exam on the course content.
Literature and other teaching material Chapters of Book Fundamentals of Inflammation (Cambridge University Press) and published review state-of-the-art articles within the relevant research area will be distributed at the start of the course.
Number of students 8 - 40
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course is run in two blocks. First 3 days of introduction and lectures 17-19 september 2018. Then 2.5 weeks project/group work, followed by 3 days of lectures and presentation of group work.
Additional course leader Course responsible: Cecilia Aulin, cecilia.aulin@ki.se Mia Olsson, mia.olsson@ki.se
Earlier evaluation of the course Not available
Course responsible Cecilia Aulin
Institutionen för medicin, Solna

cecilia.aulin@ki.se
Contact person Cecilia Aulin
Institutionen för medicin, Solna

cecilia.aulin@ki.se


Mia Olsson
Institutionen för medicin, Solna

mia.olsson@ki.se