Kurskatalog forskarutbildning - VT19

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Titel Neurodegenerative disorders II - cellular and molecular mechanisms
Kursnummer 2630
Program Neurovetenskap
Språk Engelska
Antal högskolepoäng 1.5
Datum 2018-10-15 -- 2018-10-19
Kursansvarig institution Institutionen för neurobiologi, vårdvetenskap och samhälle
Särskild behörighet The course is a continuation of the course Neurodegenerative disorders I, From molecule to treatment, but it can also be taken as a separate course, provided the participant has in other ways achieved the learning outcomes of that course.
Kursens syfte The purpose of the course is to provide a deeper understanding of neurodegenerative disorders, focusing on molecular mechanisms and techniques used for studying these, as well as treatment strategies.
Kursens lärandemål The student should:
- be able to understand and critically evaluate relevant cellular and molecular pathophysiological mechanisms of neurodegenerative disorders such as stroke, Alzheimer disease, frontotemporal dementia, Lewy body disease, Parkinson´s disease, multiple sclerosis, amyotrophic lateral sclerosis, and the mechanisms of current and/or possible future treatments.
- be able to understand and to perform important methods and assays for studying mechanisms behind neurodegenerative disorders, and discuss the results, taking into account the limitations of the assays.
- be able to discuss the present disease models, propose alternative models, and critically evaluate these models from the perspectives of a) clinical picture, b) disease mechanisms, and c) treatment mechanisms.
Kursens innehåll The course addresses topics in basic and clinical research on neurodegenerative disorders. The focus will be on a deeper understanding of cellular and molecular mechanisms, and the techniques to study them. To this end, the students will learn about some powerful techniques that can be used for studying neurodegeneration, subcellular localization, and elucidation of pathogenic pathways.
Arbetsformer The course runs daytime for 1 week full-time with some key lectures by invited scientists, laboratory practicals, and discussions in small groups and the entire class.
Obligatoriska moment The student is obliged to attend 80% of the lectures, all laboratory practicals, and the exam (including the group discussion after the exam). Students that are absent from the practicals and/or more than 20% of the lectures will have to submit a written presentation of the subjects missed.
Examination Oral examination followed by group discussions on the examination questions, and a general discussion between all participants.
Kurslitteratur och övriga läromedel Scientific articles and hand-outs distributed by the course organizers and lecturers.
Antal studenter 10 - 24
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
Övrig information The course is given at the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Bioclinicum.
Ytterligare kursledare Lars Tjernberg, Per ET Nilsson
Tidigare omdöme av kursen omdöme
Kursansvarig Sophia Schedin Weiss
Institutionen för neurobiologi, vårdvetenskap och samhälle

sophia.schedin.weiss@ki.se
Kontaktpersoner Per Nilsson
Institutionen för neurobiologi, vårdvetenskap och samhälle

Per.et.Nilsson@ki.se


Lars Tjernberg
Institutionen för neurobiologi, vårdvetenskap och samhälle

Lars.Tjernberg@ki.se