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Title Heart failure - from pathophysiology to evidence based treatment
Course number 2909
Programme Kardiovaskulär forskning
Language English
Credits 0.6
Date 2018-03-13 -- 2018-03-20
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements undergraduate study in medicine or biomedicine
Purpose of the course To provide a comprehensive overview of heart failure, a major public health problem and the most common cause of hospitalisation. The course will address all aspects of the disease, from mechanism and pathophysiology, to how these aspects affect diagnosis and therapeutic effects. The course will also introduce the new developments and future directions of heart failure research.
Intended learning outcomes To be able to define and understand heart failure and its different phenotypes; to be able to understand the pathophysiological basis for diagnosis and therapy; to be able to understand and account for concepts for developing and testing novel interventions; and to demonstrate a good understanding of translational approach between basic research and the development of treatment of heart failure, as well as the principles of registry based research on heart failure.
Contents of the course The module will cover pathophysiology, clinical diagnosis and treatments, as well as epidemiology of heart failure. A series of lectures will be given to reveal the molecular and cellular mechanisms of heart failure development, the relations of heart failure to other cardiovascular diseases, and new diagnotic and therapeutic approaches of the disease. Registry based research of heart failure will also be addressed.
Teaching and learning activities The 2-day course module includes course lectures and seminars.
Compulsory elements The participants must attend the lectures and seminars. The students who have missed these sessions can book extra session time within 4 weeks to compensate the absence.
Examination Written exam.
Literature and other teaching material The handouts/teaching materials from all lectures will be provided:
Pathology and epidemiology of heart failure
Calcium signaling of cardiomyocytes
Endothelial dysfunction in heart failure
Registry-base clinical research of heart failure and the Swedish Heart Failure Registry
Biomarkers and imaging of heart failure
Valve disease and valve interventions in heart failure
Surgical therapy and device therapy of heart failure
Number of students 8 - 20
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information Two full days. Tuesday 13th of March and Tuesday 20th of March 2018.
Additional course leader Course leaders: 1) Tonje Thorvaldsen (Tonje.thorvaldsen@sll.se) 2) Lars H Lund
Latest course evaluation Course evaluation report
Course responsible Tonje Thorvaldsen
Institutionen för medicin, Solna

tonje.thorvaldsen@ki.se
Contact person Nailin Li
Institutionen för medicin, Solna
08-51773996
Nailin.Li@ki.se

Clinical Pharmacology Unit
Karolinska University Hospital-Solna
17176
Stockholm


Lars Lund
Institutionen för medicin, Solna

Lars.Lund@ki.se