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Title Principles of toxicology
Course number 2879
Programme X- Används inte längre - Miljöfaktorer och hälsa
Language English
Credits 1.5
Date 2018-02-19 -- 2018-02-23
Responsible KI department Institutet för miljömedicin
Specific entry requirements
Purpose of the course The purpose of the course is to learn how chemical substances can have unwanted/adverse effects on living organisms and how the toxicity is studied.
Intended learning outcomes Upon completion of the course, the student should be able to:
-describe the principles of toxicology
-explain how toxicological methods are applied
-evaluate toxicological data
-reflect on the role of toxicology in biomedical research and for sustainable development
Contents of the course Toxicology is the study of unwanted/adverse effects of chemical substances on living organisms. Toxicology deals with substances such as pharmaceuticals, environmental pollutants, chemicals in cosmetics, clothing or other everyday products and pesticide residues, food additives and other substances in food.
The course introduces the history of toxicology and the tasks and scope of toxicology today in biomedical research and for a sustainable society. It moves on to the general principles of toxicology, including exposure to chemicals, absorption, distribution and elimination of chemicals, toxic effects on different organs and the role of dose-response relationships. Thereafter the application of in vivo, in vitro and in silico toxicological methods is discussed. Ethical principles of toxicological studies are addressed. Toxicological data from different methods is analysed using examples from toxicological research studies. The participants will discuss how their own research questions can relate to toxicological research.
Teaching and learning activities Teaching and learning activities include lectures, exercises and group assignments.
Compulsory elements Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Literature and other teaching material Klaassen, C.D., Casarett & Doull's Essentials of Toxicology. McGraw-Hill Professional, 2015, 3rd Rev ed.
Number of students 8 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information
Additional course leader Course directors: Charlotte Nilsson, Swetox and Johanna Zilliacus, Institute of Environmental Medicine
Latest course evaluation Course evaluation report
Course responsible Charlotte Nilsson
Institutet för miljömedicin

charlotte.nilsson@ki.se
Contact person Johanna Bergman
Institutet för miljömedicin

johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm