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| Titel | Principles of toxicology |
|---|---|
| Kursnummer | 2879 |
| Program | X- Används inte längre - Miljöfaktorer och hälsa |
| Språk | Engelska |
| Antal högskolepoäng | 1.5 |
| Datum | 2018-02-19 -- 2018-02-23 | Kursansvarig institution | Institutet för miljömedicin |
| Särskild behörighet | |
| Kursens syfte | The purpose of the course is to learn how chemical substances can have unwanted/adverse effects on living organisms and how the toxicity is studied. |
| Kursens lärandemål | Upon completion of the course, the student should be able to: -describe the principles of toxicology -explain how toxicological methods are applied -evaluate toxicological data -reflect on the role of toxicology in biomedical research and for sustainable development |
| Kursens innehåll | Toxicology is the study of unwanted/adverse effects of chemical substances on living organisms. Toxicology deals with substances such as pharmaceuticals, environmental pollutants, chemicals in cosmetics, clothing or other everyday products and pesticide residues, food additives and other substances in food. The course introduces the history of toxicology and the tasks and scope of toxicology today in biomedical research and for a sustainable society. It moves on to the general principles of toxicology, including exposure to chemicals, absorption, distribution and elimination of chemicals, toxic effects on different organs and the role of dose-response relationships. Thereafter the application of in vivo, in vitro and in silico toxicological methods is discussed. Ethical principles of toxicological studies are addressed. Toxicological data from different methods is analysed using examples from toxicological research studies. The participants will discuss how their own research questions can relate to toxicological research. |
| Arbetsformer | Teaching and learning activities include lectures, exercises and group assignments. |
| Obligatoriska moment | Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task. |
| Examination | Examination is in the form of a written assignment and/or oral presentation. |
| Kurslitteratur och övriga läromedel | Klaassen, C.D., Casarett & Doull's Essentials of Toxicology. McGraw-Hill Professional, 2015, 3rd Rev ed. |
| Antal studenter | 8 - 30 |
| Urval av studenter | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date) |
| Övrig information | |
| Ytterligare kursledare | Course directors: Charlotte Nilsson, Swetox and Johanna Zilliacus, Institute of Environmental Medicine |
| Senaste kursvärdering | Kursvärderingsrapport |
| Kursansvarig |
Charlotte Nilsson Institutet för miljömedicin charlotte.nilsson@ki.se |
| Kontaktpersoner |
Johanna Bergman Institutet för miljömedicin johanna.bergman@ki.se Nobels väg 13 17177 Stockholm |
