Kurskatalog forskarutbildning - HT18

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Titel Health risk assessment: principles and applications
Kursnummer 1561
Program Miljöfaktorer och hälsa
Språk Engelska
Antal högskolepoäng 1.5
Datum 2018-03-12 -- 2018-03-16
Kursansvarig institution Institutet för miljömedicin
Särskild behörighet
Kursens syfte The purpose of this course is to build knowledge and understanding of the scientific method to assess risks to humans of exposure to different types of chemicals.
Kursens lärandemål Upon completion of the course, the student should be able to:
-describe the basic concepts and principles of health risk assessment of chemical substances
-explain how different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data are used in risk assessment
-assess the relevance and reliability of data used in risk assessment
-derive health based guidance values such as Acceptable Daily Intake (ADI) based on the data
-reflect on the role of health risk assessment in regulatory decision making
Kursens innehåll Health risk assessment of chemicals is the scientific method to assess the risk to humans of exposure to different types of chemical substances, such as pharmaceuticals, environmental pollutants, chemicals in cosmetics, clothing or other everyday products and pesticide residues, food additives and other substances in food. The course starts off with introducing the concepts in risk assessment, e.g. aims of risk assessment, role of risk assessment in risk analysis (risk assessment, risk management, risk communication), different steps in risk assessment (hazard identification, hazard characterisation, exposure assessment, risk characterisation). It moves on to the different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data that are used in risk assessment. Thereafter it is discussed how the relevance and reliability of the data is assessed, and how different types of evidence are integrated (for example from animal and epidemiological studies). The principles on how to derive health-based guidance values such as Acceptable Daily Intake (ADI) and to derive Margins of Safety values based on the data are exercised. The course then moves on to provide examples of the role of risk assessment in regulatory decision making. Case studies of different types of risk assessments exemplify how research connects to risk assessment activities. The participants will also discuss how their own research can contribute to risk assessments.
Arbetsformer Teaching and learning activities include lectures, exercises and group assignments.
Obligatoriska moment Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Kurslitteratur och övriga läromedel Health risk assessment reports and guidelines from international organisations.
Antal studenter 8 - 30
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
Övrig information
Ytterligare kursledare Course directors: Anna Beronius, Annika Hanberg and Johanna Zilliacus
Tidigare omdöme av kursen omdöme
Kursansvarig Anna Beronius
Institutet för miljömedicin

anna.beronius@ki.se
Kontaktpersoner Johanna Bergman
Institutet för miljömedicin

johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm