Course catalogue doctoral education - VT18

  • Ansökan kan ske mellan 2017-10-16 och 2017-11-15
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Title Biobanking as a resource for biomedical research
Course number 2714
Programme 0-Inte del av forskarutbildningsprogram
Language English
Credits 1.5
Date 2018-03-12 -- 2018-03-16
Responsible KI department Institutionen för medicinsk epidemiologi och biostatistik
Specific entry requirements Nej
Purpose of the course This course aims to provide practical knowledge to start biobanking with state of the art quality comprising ethics, legal aspects, sampling handling and logistics. Furthermore the course aims to enable the course participants to get insight in and knowledge about how to collect human tissue samples and associated data, about how to apply technology advancements such as next generation sequencing, proteomics and metabolomics to harness biological information from biobanked material such as tissues and liquid biopsies and finally to get insight into successful research projects where biobanking in combination with large scale analysis is having direct impact on health care. .
Intended learning outcomes At the end of the course the student should:
- Understand the value of biobanks and be able to explain how to use these rich sources of samples and related data.
- Understand the legal and ethical framework related to biobanks and how to utilize biobanked samples in future national and international projects,
- Have insight and knowledge about how to start a new study and understand the impact of quality and standardization on downstream applications,
- Understand and explain the need for a secure IT structure in order to ensure the sample donors integrity with a full traceability of samples and data,
- Discuss own or other's research projects related to biobanked samples.
Contents of the course 1. Practical knowledge to enable biobanking including - Ethical and Legal aspects - IT infrastructure - Required documentation and stakeholders - Biobank service; available infrastructures 2. How to biobank with high quality from various sources such as: - Blood/plasma/serum/urine - PBMC - Single cells - Tissues 3. Examples of how to apply molecular technologies to harness information - Proteomics of plasma and tissues - Metabolomics of plasma, serum and urine - Sequencing of circulating tumor DNA/RNA - Single cell sequencing of circulating tumor cells and tissues - DNA and RNA sequencing of tumor tissues - Epigenetics of blood and tissues 4. The value of applying quality registries to biobanked material
Teaching and learning activities - Lectures - Exercises - Field trip (visiting a biobank) - Final seminar with presentations and discussions about the course assignment (either a pre-defined biobank study or an example from own research)
Compulsory elements Taking part in all scheduled activities: lectures, field trip and presentation/examination. Compensation according to the instructions of the course director.
Examination Presentation and discussion of the course assignments, either a pre-defined biobank study or an example from own research. All learning outcomes will be covered.
Literature and other teaching material Scientific articles that will be referred to during the course. Webpages:
Number of students 15 - 25
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date).
More information Monday - Friday 9:00-16:00 Venue: Wargentin, Dept of medical epidemiology and biostatistics, Campus Solna.
Additional course leader Johan Lindberg.
Earlier evaluation of the course Evaluation report
Course responsible Gunnel Tybring
Institutionen för medicinsk epidemiologi och biostatistik
Contact person Johan Lindberg
Institutionen för medicinsk epidemiologi och biostatistik