Course catalogue doctoral education - VT24
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| Title | Advanced Cell Culture - modelling with human induced pluripotent stem (iPS) cells |
|---|---|
| Course number | 3025 |
| Programme | Tumörbiologi och onkologi (FoTO) |
| Language | English |
| Credits | 3.0 |
| Date | 2018-01-22 -- 2018-02-02 | Responsible KI department | Institutionen för neurovetenskap |
| Specific entry requirements | |
| Purpose of the course | The purpose of the course is to give students training on advanced cell culturing and how to implement them in medical research for cancer treatment and regenerative medicine. The participants will be given the opportunity to develop basic hands-on skills in how to culture human iPS cells and other human cell types |
| Intended learning outcomes | After the course, the student is expected to: - Be able to describe the basic knowledge on how to culture human induced pluripotent stem (iPS) cells. - Be able to critically assess how cultured cells can be used in therapies today. - Understand organoid culturing and their role in medical research. - Acquire basic knowledge on tissue engineering and critically assess their future implementation in research. - Discuss how cell cultures can be developed in medical research and how to implement their use within the frame of their current and future research activities. |
| Contents of the course | The course covers a wide variety of topics involving cell culturing, including; sources (human) of cells for culturing, growth conditions, monitoring, basic quality analysis of cells in culture, culturing of cells in monolayers, as organoids and in co-cultures with other cells types. Strong emphasis will be given to practical hands-on sessions. Throughout the course, the concept of good manufacturing practice (GMP) for human cell cultures and the practical use of cell cultures for disease modeling, regenerative medicine and cancer treatment will be strongly implemented. |
| Teaching and learning activities | To provide a comprehensive and practical hands course, several teaching activities will be combined during the course, including lectures, laboratory practice, group discussion, presentation of a research proposal and study visit to laboratory implementing human cell cultures in production. |
| Compulsory elements | Laboratory practice, group tasks and presentations are mandatory |
| Examination | The course assignment will consist on a formative assessment based on individual presentation of a research proposal. The proposal is focusing on the study design of the cell culture experiments demonstrating that they can design a cell culture experiment and put cell culturing into context of a specific scientific question, related to their scientific activities. The course organizers will lead the examination, providing feedback during the presentation in line with the concept of formative assessment, and they will be further responsible for the summative individual assessment. |
| Literature and other teaching material | Relevant research articles will be provided during the course. |
| Number of students | 8 - 16 |
| Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant¿s doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date) |
| More information | Lectures will be held at the department of Neuroscience in Solna. Hands-on cell culturing will be performed at the MTC course lab in Solna. |
| Additional course leader | Anna Falk (Anna.Falk@ki.se) Malin Kele (Malin.Kele@ki.se) |
| Latest course evaluation | Not available |
| Course responsible |
Anna Falk Institutionen för neurovetenskap Anna.Falk@ki.se |
| Contact person |
Malin Kele Institutionen för neurovetenskap Malin.Kele@ki.se |
