Kurskatalog forskarutbildning - HT18

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Titel Adverse outcome pathways (AOPs)-principles and applications in toxicology and health risk assessment
Kursnummer 2986
Program Miljöfaktorer och hälsa
Språk Engelska
Antal högskolepoäng 1.5
Datum 2017-11-06 -- 2017-11-10
Kursansvarig institution Institutet för miljömedicin
Särskild behörighet
Kursens syfte The purpose of the course is to enable the acquirement of knowledge and understanding in how the concept of Adverse outcome pathways (AOPs) can provide a framework for research in toxicology and for applications for health risk assessment. An AOP is a description of a sequence of events starting with the interaction of a chemical with a biomolecule in a target cell or tissue (molecular initiating event), progressing through key events and ending in an adverse outcome.
Kursens lärandemål At the end of the course the student should be able to:
describe the principles and components of Adverse Outcome Pathways (AOPs)
explain how experimental studies can support the development of AOPs
discuss how AOPs can be used as a central framework for mechanistic toxicity studies, toxicity testing and health risk assessment
Kursens innehåll The course will include the concept and principles of Adverse Outcome Pathways (AOPs). Development and assessment of AOPs. Examples of different AOPs. Application of the AOP concept in toxicological research and health risk assessment.
Arbetsformer Teaching and learning activities include lectures, exercises and group assignments.
Obligatoriska moment Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Kurslitteratur och övriga läromedel Scientific publications and reports from international organisations.
Antal studenter 8 - 14
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
Övrig information The course is held at KI Campus Solna
Ytterligare kursledare Course directors: Johanna Zilliacus and Annika Hanberg, Institute of Environmental Medicine (IMM), Karolinska Institutet.
Tidigare omdöme av kursen Not available
Kursansvarig Johanna Zilliacus
Institutet för miljömedicin
08 52483544
Kontaktpersoner Johanna Bergman
Institutet för miljömedicin


Nobels väg 13