Kurskatalog forskarutbildning - VT18

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Titel Methods in molecular biology and their applications in medical research
Kursnummer 2418
Program Metabolism och endokrinologi
Språk Engelska
Antal högskolepoäng 3.0
Datum 2017-09-04 -- 2017-09-15
Kursansvarig institution Institutionen för laboratoriemedicin
Särskild behörighet
Kursens syfte The aim of this course is to confer knowledge of how basic molecular biology and protein work can be applied in clinically oriented research. The course is designed for doctoral students with limited experience of molecular biology and combines a lecture program with laboratory work. The course combines theoretical knowledge with hands-on practice.
Kursens lärandemål After the course, the students will understand the principles, from both a theoretical and practical viewpoint, of a number of basic techniques used in DNA/protein research and their application in medical research. The students should also be able to design and perform investigations with some of the discussed techniques.
Kursens innehåll The lectures will include theoretical and practical aspects on basic concepts concerning techniques in molecular biology and proteomics and their application in medical research. Specified subjects will include cloning, RNA-analysis, promoter studies, DNA-sequencing, expression, bioinformatics, antibody-based protein detection and proteomics. The overall objective is to convey knowledge of possibilities and limitations with different techniques and introduce valuable methodology for the students' PhD-projects.
Arbetsformer The course combines a lecture program in the morning with laboratory work in the afternoon, where course participants will be subdivided into smaller groups.
Obligatoriska moment Laboratory work is compulsory. To compensate for absence, self-studies and a written essay on the topic(s) that they have missed must be performed.
Examination The students will be asked to solve a scientific problem using methods they learned during the course. The last day of the course, the participants will give a presentation. They should be able to defend the laboratory design, discuss methodologies applied and anticipated results. The students will work in pairs. The task will be given to the participants at the end of the first week. Every doctoral student will be individually assessed.
Kurslitteratur och övriga läromedel Reprints and articles will be provided by the course administrators and the responsible lecturers.
Antal studenter 8 - 16
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
Övrig information
Ytterligare kursledare
Tidigare omdöme av kursen omdöme
Kursansvarig Tomas Jakobsson
Institutionen för laboratoriemedicin

Tomas.Jakobsson@ki.se
Kontaktpersoner Veronika Tillander
Institutionen för laboratoriemedicin

Veronika.Tillander@ki.se