Course catalogue doctoral education - VT24
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| Title | Regenerative Medicine: Principles to Practice |
|---|---|
| Course number | 2888 |
| Programme | Utveckling och regeneration (DevReg) |
| Language | English |
| Credits | 3.0 |
| Date | 2017-04-05 -- 2017-06-14 | Responsible KI department | Institutionen för medicin, Solna |
| Specific entry requirements | None. |
| Intended learning outcomes | After completion of this course, the student will be able to describe the basics of stem cell biology and provide an appreciation for novel approaches and applications in regenerative medicine. The student will be able to demonstrate an interdisciplinary understanding of central concepts in stem cells and critically evaluate the potential, advantages and drawbacks of different methods that are currently researched in the fields of stem cell and regenerative therapy. The student will be able to extract and integrate information from state-of-the-art lectures, scientific articles and literature search within the field. |
| Contents of the course | The course covers principles of stem cell biology and provides an appreciation for applications in regenerative medicine. Lectures and journal club-based topics include fundamental features of stem cell platforms, as well as the use of these and other platforms in the design and development of regenerative therapies. The course will exemplify how regenerative therapies can be targeted to different organs (e.g. within the cardiovascular system and the nervous system) with particular emphasis on the state-of-the-art technologies, prospects for clinical translation and current challenges within the field. The student will be required to take an active part in this course by contributing in journal clubs and discussions related to stem cell-based regenerative medicine. |
| Teaching and learning activities | The pedagogic frame of this course is based on lectures combined with topic-related research articles. Approximately half of the lectures will take place at KI (Huddinge and Solna campus). The other lectures will take place at Mayo Clinic and will be projected to students at KI via video conferencing. The course includes journal clubs where the students are required to present articles (written and orally), integrate the knowledge acquired from lectures and reading of the articles, and actively discuss their acquired knowledge as a group. Some journal clubs will be carried out in groups using interactive e-platforms. The examination task consists of a written report that is handed in for evaluation toward or at the completion of the course. |
| Compulsory elements | Active participation in lectures and journal club-based discussions is mandatory. Compensation according to the instructions of the course director. |
| Examination | The examination consists of a written report that is handed in for evaluation at the end of the course. All students are also required to peer-review another student's examination report. The individual performance of each student will be evaluated separately. |
| Literature and other teaching material | The course literature will consist of recent original and review papers on selected topics within the field of regenerative therapy. Examples of articles: 1. Arenas E (2010) Towards stem cell replacement therapies for Parkinson's disease. Biochemical and biophysical research communications 396: 152-6. 2. Badylak SF, Weiss DJ, Caplan A, Macchiarini P (2012) Engineered whole organs and complex tissues. Lancet 379: 943-52. 3. Barnabe-Heider F, Frisen J (2008) Stem cells for spinal cord repair. Cell stem cell 3: 16-24. 4. Passier R, van Laake LW, Mummery CL (2008) Stem-cell-based therapy and lessons from the heart. Nature 453: 322-9. 5. Xu Y, Shi Y, Ding S (2008) A chemical approach to stem-cell biology and regenerative medicine. Nature 453: 338-44. |
| Number of students | 6 - 12 |
| Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date) |
| More information | The course will be held once a week, every Wednesday 15.00-17.00. We will have speakers from KI and from Mayo Clinic (USA). We will hold joint sessions with Mayo Clinic via video-conferencing and you will have the opportunity to interact with students and speakers from both institutions. |
| Additional course leader | |
| Latest course evaluation | Course evaluation report |
| Course responsible |
Natalia Landazuri Institutionen för medicin, Solna natalia.landazuri@ki.se |
| Contact person |
Natalia Landazuri Institutionen för medicin, Solna natalia.landazuri@ki.se |
