Course catalogue doctoral education - VT24
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| Title | Multifactorial immune mediated diseases - etiology and pathogenesis |
|---|---|
| Course number | 2532 |
| Programme | Allergi, immunologi och inflammation (Aii) |
| Language | English |
| Credits | 1.5 |
| Date | 2016-03-07 -- 2016-03-11 | Responsible KI department | Institutionen för medicinsk biokemi och biofysik |
| Specific entry requirements | Basic knowledge in Immunology is required |
| Intended learning outcomes | After completion of the course the students should be able to explain the term multifactorial immune mediated diseases (e.g. allergic, autoimmune, and inflammatory) and discuss basic clinical characteristics and disease mechanisms. They should be able to discuss the role of environment and genes in the etiology of such diseases, and in particular that the diseases are genetically complex. The students should also be able to describe some genetic strategies aimed at identifying risk genes. They should be able to explain how identification of risk genes can give insight into disease pathways, and discuss how such knowledge may enable disease prevention and therapy. |
| Contents of the course | The course includes an overview on chronic immune mediated multifactorial diseases and the challenge they represent to medicine. It covers topics such as clinical characteristics, suggested or known disease mechanisms and genetics including experimental animal models available to study such multifactorial and polygenetic diseases. Key concepts and techniques within each topic will be introduced. |
| Teaching and learning activities | Each day, the course combines a set of overview lectures on clinical diseases followed by lectures on pre-clinical experimental models. Everyday afternoon a group discussion will be held based on previously provided publication (one per day), at group level to facilitate peer learning. One to two senior scientists will facilitate the discussion by providing specific questions related to the publication. The tasks generally consists of ""scientific projects"" that are pursued by combining knowledge acquired during lectures with information available in the literature. |
| Compulsory elements | All lectures, seminars and group- or individual- tasks are compulsory. Compensation for absence can be discussed with the course director. |
| Examination | Examination is based on interactive engagement during daily discussions in the afternoon sessions on all days. During last day, each student should prepare, present and discuss questions (minimum: 3-5) based on earlier presentations and published papers given during the course with their group members (peer-learning), which will be facilitated by two senior scientists. Apart from the oral presentation, written assignment for two pages connecting the lectures with their own work will be asked from all the participants to Pass the course. Participants should send this written assignment within 5 working days after the last date of the course. |
| Literature and other teaching material | Course litterature consists of lecture handouts and selected scientific publications given during the course. In addition, the following books are recommended but not compulsory: Human Molecular Genetics (2004), by Strachan and Read or later editions Janeway's immunobiology (2012) eighth edition, Kenneth Murphyp; Paul Travers; Mark Walport; Charles Janeway Above-mentioned books are available in Karolinska Institute Library. |
| Number of students | 12 - 16 |
| Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date) |
| More information | Course will be for 5 days. Course will start on 7th March 2016 at 08:30 and will be up to 16:30 but on all other days from 09:00 to 16:30. All the activities will be held in A3311 (Stora Seminarierummet) except two lectures on 8th and 9th that will be conducted in A2 317 (Seminar Room). These two seminar rooms are located in the Department of Medical Biochemistry and Biophysics, Scheeles väg 2, Solna Campus, Karolinska Institutet. |
| Additional course leader | |
| Latest course evaluation | Course evaluation report |
| Course responsible |
Nandakumar Kutty Selva Institutionen för medicinsk biokemi och biofysik 08-52487715 Nandakumar.Kutty-Selva@ki.se Scheelesvag 2, B2, plan 4 17177 Stockholm |
| Contact person | - |
