Kurskatalog forskarutbildning - HT18

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Titel Regulatory RNAs in Development, Disease and Evolution
Kursnummer 2865
Program 1-Ingår i flera program
Språk Engelska
Antal högskolepoäng 2.0
Datum 2015-10-07 -- 2015-10-16
Kursansvarig institution Institutionen för medicinsk biokemi och biofysik
Särskild behörighet -
Kursens lärandemål After completing the course, the students should be able to:

- describe the different kinds of regulatory RNAs in development, disease and evolution, and their mechanism of action
- describe and critically evaluate the application of emerging experimental strategies for the study of regulatory RNAs
- transfer the knowledge acquired in the course into their specific projects and fields of research.
Kursens innehåll The course will cover key concepts concerning regulatory RNAs and their mechanisms of action. The following themes will be covered: Different kinds of regulatory (non-coding) RNAs in eukaryotes, regulatory RNAs in development and disease, regulatory RNAs in virus and bacteria, evolution of regulatory RNAs, RNA dynamics and RNA methodologies (bioinformatics and emerging experimental strategies).
Arbetsformer The learning activities include lectures, seminars, group discussions and presentations. The students will present themselves with short chalk talks on the first day. They will be divided into groups and will have several sessions designated for groups discussions and brainstorming to transfer and apply the new knowledge acquired during the course into their specific projects and fields of research. Each group will present and discuss their conclusions from these discussions to all the other students and course directors.
Obligatoriska moment Lectures, seminars, group discussions and presentations are mandatory. Compensation in case of absence according to the instructions of the course director.
Examination Examination according to the intended learning outcomes of the course will take place in form of a presentation, where the course participants will discuss the transfer of the knowledge acquired during the course into their specific projects and fields of research. Each course participant will be assessed individually.
Kurslitteratur och övriga läromedel Scientific articles according to the recommendations from the lecturers and course organisers.
Antal studenter 15 - 30
Urval av studenter The selection is based on relevance of the course content for their doctoral project and the personal motivation included in the course application.
Övrig information The course is full time. Most of the course lectures will be given at the main seminar room at the Scheele building, Department of Medical Biochemistry and Biophysics (A3 311). The students will participate in a Karolinska Institutet conference on Regulatory RNAs and Chromatin at the Nobel Forum, October 16th 2015, with the following speakers confirmed: Leonie Ringrose, Institute of Molecular Biotechnology, Vienna, Austria, Johan Jakobsson, Lund University, John Rinn, Harvard University, USA, Raffaella Santoro, University of Zurich, Switzerland, Marcel Dinger, Garvan Institute of Medical Research, Sidney, Australia and Tony Kouzarides, University of Cambridge, United Kingdom. The course is jointly organized by Karolinska Institutet and Uppsala University and co-funded by the doctoral programme in Regenerative medicine, doctoral programme in Cell Biology and Genetics (see https://internwebben.ki.se/en/doctoral-programmes-0) and DBRM (www.dbrm.se).
This course has previously been given as a one week course (1,5 hp), course number 2698.
Ytterligare kursledare The course directors are: Gonçalo Castelo-Branco, Karolinska Institutet (Goncalo.Castelo-Branco@ki.se), Andrea Hinas, Uppsala University (andrea.hinas@imbim.uu.se) and Paulo Amaral, University of Cambridge, United Kingdom (p.amaral@gurdon.cam.ac.uk).
Tidigare omdöme av kursen omdöme
Kursansvarig Goncalo Castelo-Branco
Institutionen för medicinsk biokemi och biofysik

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