Kurskatalog forskarutbildning - VT24

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Titel Study design in clinical research
Kursnummer 1794
Program 0-Inte del av forskarutbildningsprogram
Språk Engelska
Antal högskolepoäng 4.0
Datum 2015-11-16 -- 2015-12-04
Kursansvarig institution Institutionen för molekylär medicin och kirurgi
Särskild behörighet
Kursens lärandemål After completion of the course the students should be able to:
1) Independently plan and produce a study protocol including a thorough methodological evaluation and choice of appropriate study design.
2) Critically reflect on other students individual project work in a scientifically constructive way.
3) Interpret and critically evaluate scientific studies relevant to the course content.

Kursens innehåll The course is designed for PhD-students, in particular those who are at an early stage of their research education, and those with an interest in conducting clinical research. The content of the course is as follows: 1) Basic terms in epidemiology and clinical study design, 2) Measures of disease occurrence and incidence, causality, 3) Observational studies- cohort and case-control studies, 4) Systematic and random errors, 5) Experimental studies, randomised clinical trials, 6) Quality of life in clinical research, 7) Examination and course evaluation. Throughout the course, the students will work on an individual project (examination 1) for peer-review (examination 2). Further, students will critically review and discuss relevant scientific articles (examination 3).
Arbetsformer Lectures, seminars, individual article review, group discussions and homework tasks will be used. The course focuses on active learning, i.e. putting knowledge into practice and critically reflecting upon the knowledge, rather than memorising facts. Therefore, much of the focus of the course is on the individual project where students are required to develop a full study protocol including several important aspects covered in the lectures, article reviews and group discussions. Students will also peer-review eachothers projects and this will form the basis for the final examination seminar.
Obligatoriska moment Compulsory attendance includes the scheduled lectures and seminars. Absence will need to be replaced by individual assignments following discussion with the course co-ordinator, e.g. article reviews, with written or oral follow-up.
Examination To pass the course the student must actively participate in the course and pass the examinations: 1) Individual project work: To develop a written comprehensive yet concise study protocol including several important aspects study design as discussed during the course; 2) Peer-review of other students projects followed by oral presentation own project and opposition of other students projects during the group examination; 3) Critically review scientific articles relevant to the course content and participate actively in the seminars.
Kurslitteratur och övriga läromedel Mandatory: Kenneth J Rothman ""Epidemiology -an introduction"" (2012) Oxford University Press, USA.
Scientific articles (handed out during course).
Antal studenter 18 - 25
Urval av studenter Selection will be based on 1) Date of registration as a PhD student 2) suitability of PhD project 3) The motivation to attend the course.
Övrig information
Ytterligare kursledare
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Nele Brusselaers
Institutionen för mikrobiologi, tumör- och cellbiologi
0761516212
nele.brusselaers@ki.se

CTMR - Nobelsvag 16 - KISolna

17177
Stockholm
Kontaktpersoner Kalle Mälberg
Institutionen för molekylär medicin och kirurgi

kalle.malberg@ki.se