Catalogue courses on doctoral level - HT13
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| Title | Neurodegenerative disorders I - From molecule to treatment |
|---|---|
| Course number | 2629 |
| Program | Neurovetenskap |
| Language | English |
| Credits | 1.5 |
| Date | 2012-09-24 -- 2012-09-28 |
| Level | Forskarnivå |
| Responsible KI department | Institutionen för neurobiologi, vårdvetenskap och samhälle |
| Specific entry requirements | |
| Learning outcomes | The student should: Understand the cellular processes and molecular mechanisms of neurodegeneration. Understand mechanisms of protein turnover and degradation, and protein aggregation, and from these mechanisms critically evaluate the concept of conformational disorders, and its relevance to the different neurodegenerative disorders. Have achieved basic knowledge about epidemiology, symptoms, pathology and current treatments of the most common neurodegenerative disorders such as stroke, Alzheimer¿s disease, frontotemporal dementia, Lewy body disease, Parkinson¿s disease, multiple sclerosis, amyotrophic lateral sclerosis, ataxias, prion diseases, epilepsy and trauma. Understand how the pathology of these disorders is reflected in their symptoms. Based on this understanding, be able to discuss the effects of treatments, if they are (or may be) symptomatic or curative. Be able to evaluate the relevance of different disease models, their advantages and limitations with respect to the clinical picture and to what is known about disease mechanisms. |
| Contents of the course | The course will cover topics related to the degeneration of neurons, apoptosis and necrosis, and the cellular and biochemical reactions to neuronal injury. The teachers will also present and discuss symptoms, diagnosis, pathology, epidemiology, genetics and treatment of neurodegenerative disorders such as stroke, Alzheimer's disease, frontotemporal dementia, Lewy body disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, ataxias, prion diseases, epilepsy and trauma. Molecular mechanisms of current and future treatment strategies, disease models and their potential, will be presented and discussed. |
| Type of teaching | The course runs daytime for 1 week full-time with lectures by invited scientists, literature seminars as group assignments, and individual studies. |
| Examination | Written examination followed by group discussions on the examination questions, and a general discussion between all participants. |
| Compulsory elements | Literature seminars and the exam (including the group discussion after the exam) are compulsory. Students that are absent from literature seminars will have to submit a written presentation of the subject. |
| Number of students | 10 - 30 |
| Selection of students | In case too many students apply, selection of participants will be based on how relevant the course content is to the student's study plan |
| More detailed information | This course is part of the Series of FRONTIERS IN NEUROSCIENCE COURSES. The course is given at Novum, Huddinge. |
| Course directors | Marianne Schultzberg |
| Earlier evaluation of the course | Not available |
| Syllabus coordinator |
Erik Sundström Institutionen för neurobiologi, vårdvetenskap och samhälle 0858583887 Erik.Sundstrom@ki.se |
| Contacts | - |
